Gainesville Area Chamber of Commerce- (352) 334-7100. Since 1924, the Gainesville Area Chamber has been a strong advocate for the area’s business and professional community through a sharp focus on critical issues and initiatives that aid growth and prosperity. The Chamber provides a forum to strengthen businesses via a wide range of member services including networking and marketing opportunities, advisory committees and community involvement, and advocacy. With a membership of more than 1,400 businesses representing 75,000 employees, the Chamber can accomplish collectively what no one business can do alone.